Source: Sharecast
"Sean is a practising chief executive and an outstanding business leader in the complex and challenging airline industry," M&S said. "He also represents an iconic British brand with extraordinary public exposure."
Roger Burnley, former CEO of Asda, will also join the board on 1 December, while Archie Norman's tenure as chair will be extended.
M&S said this renewal was part of a broader programme to refresh the board as it embarks on "the next phase of the Reshaping for Growth strategy".
Sean Doyle said: "Being the CEO of Britain's flag carrier is a very special job, as you are the custodian of a brand which is part of the fabric of the country. Not many brands can equal that, but M&S certainly can.
"I am privileged to be joining a board focused on 'protecting the magic' of the brand as it modernises the business through the Reshaping for Growth strategy and look forward to supporting the next phase."